TEXTBOOK OF STRUCTURAL BIOLOGY LILJAS PDF
BOOK REVIEW Textbook of Structural Biology, by Anders Liljas, Lars Liljas, Jure Piskur, Go¨ran Lindblom, Poul Nissen, and Morten Kjeldgaard. Textbook of Structural Biology, by Anders Liljas, Lars Liljas, Jure Piskur, Göran Lindblom, Poul Nissen, and Morten Kjeldgaard. The burgeoning field of structural biology is most succinctly described by stating that there are now more than 50, biological macromolecular 3-D structures.
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Latest Edition: Textbook of Structural Biology (2nd Edition). This is an important textbook for Textbook of Structural Biology. Anders Liljas et al., World Scientific. Library of Congress Cataloging-in-Publication Data. Names: Liljas, Anders, author. Title: Textbook of structural biology / Anders Liljas, Lund University, Sweden. Textbook of Structural Biology By Anders Liljas, Lars Liljas, Jure Piskur, Göran Lindblom, Poul Nissen, and Morten Kjeldgaard Publisher: World.
The recently published, paged, book by Liljas et al. It contained much of the essential background knowledge on protein structure and described some of the first protein structures oxygen-carrying globins, electron transporting cytochrome, proteinases, and nucleases that had been studied in three-dimensional atomic detail. It was essential reading for anyone interested in protein structure and function. Now, in , we have a new successor to this series that is better and bigger than any of its predecessors. Knowledge of structure has expanded exponentially.
Although the book is copiously illustrated in beautifully executed, colored, computer-drawn figures, some of the mechanistic explanations could have been clearer by the use of easily understood chemical symbols. For instance, the book lacks a series of simple figures explaining the action of the ser-his-asp catalytic triad in proteinases such as trypsin. It would appear that we cannot yet discard our worn out volumes of Dickerson and Geiss.
The amount of information compressed into less than pages is a great achievement and essential for those who wish to understand biological processes at a basic level of molecules, atoms, and their chemistry. National Center for Biotechnology Information , U.
Textbook of Structural Biology
Journal List Protein Sci v. Protein Sci. Reviewed by Michael Rossmann.
Author information Article notes Copyright and License information Disclaimer. Received Oct 2. References 1. Textbook of Structural Biology. World Scientific Publishing; Dickerson RE, Geiss I. The Structure and Action of Proteins.
New York: Harper and Row; Principles of Protein Structure.
Textbook of Structural Biology
Springer-Verlag; Branden C-I, Tooze J. Introduction to Protein Structure. Garland Publishing; Wilson HR. Edward Arnold Publishers ; Perutz MF. Proteins and Nucleic Acids.
Some readers might have liked a more complete set of references to original work, although forming an unbiased index to the relevant literature must be an almost impossible task without hurting feelings of priority and maintaining relevance to the topic. A novel and useful feature is the technical appendages A through F on, for instance, prediction of secondary structure and on assignment of function.
Nevertheless, at times the discussion seems a bit vague as, for example, the discussion of Table A. This table shows that single, double, and triple carbon—carbon bonds are progressively shorter.
Carbon—carbon bonds of order 1. However, the reference to quantum mechanical calculations and the ordering in the table itself obscures the fact that this table was derived experimentally.
Liljas et al.
Finally, the relationship between function, structure, and evolution emerges clearly from the previous discussion. The subsequent chapter on nucleic acid conformation follows the same pattern, starting with the restriction on conformational angles in sugars, secondary structure of DNA and RNA, bulges, junctions and pseudoknots, and culminating with the structure of tRNAs, ribosomes, and ribozymes.
Chapter 5 to the final Chapter 16 cover various basic biological processes such as enzymatic catalysis, transcription, translation, apoptosis, protein folding, signal transduction, motility, and immunology with a final chapter on virus structure.
It would appear that we cannot yet discard our worn out volumes of Dickerson and Geiss. The amount of information compressed into less than pages is a great achievement and essential for those who wish to understand biological processes at a basic level of molecules, atoms, and their chemistry.
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